Bone disease biomarkers

RBM offers a number of biomarkers that have utility in bone diseases, such as osteoporosis and Paget's diease.

C-Reactive Protein (CRP), Osteocalcin, Bone-specific alkaline phosphatase (BSAP), C-Terminal Telopeptide (CTX), N-Terminal Telopeptide (NTX), Procollagen Type I N-Propeptide (PINP), RANKL, Osteoprotegerin (OPG), Sclerostin, and Dickkopf-1 (DKK1), are crucial in diagnosing and monitoring bone diseases like osteoporosis. These biomarkers reflect bone formation, bone resorption, and regulatory processes, providing insights into bone metabolism and turnover. For instance, CRP indicates inflammation that can affect bone health, while Osteocalcin and BSAP are markers of bone formation. CTX and NTX measure bone resorption, and PINP indicates new bone formation. RANKL, OPG, Sclerostin, and DKK1 are involved in bone remodeling regulation, helping to identify potential therapeutic targets and monitor treatment efficacy.

Multiplexes with bone disease biomarkers

• Discovery MAP
• Human MAP