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Autoimmune disease biomarkers
Biomarkers by Therapy Indication
- Autoimmune Disease and Arthritis Biomarkers
- Bone Disease Biomarkers
- Cancer Biomarkers
- Cardiovascular Biomarkers
- Cytokine and Chemokine Biomarkers
- Diabetes and Metabolic Biomarkers
- Endocrine Biomarkers
- Gastrointestinal Biomarkers
- Neuroscience Biomarkers
- Inflammation and Immune Response Biomarkers
- Kidney Function and Toxicity Biomarkers
RBM offers dozens of biomarkers with demonstrated correlation to autoimmune conditions. Autoimmune illnesses occur when the immune system mistakenly attacks the body's own tissues, causing inflammation and tissue damage. With more than 100 different autoimmune conditions affecting millions of people, this represents an important and growing area for biomarker research.
Our biomarkers reflect various aspects of immune system activity, inflammation, and tissue damage, aiding in the identification of disease activity and therapeutic responses. For instance, Interleukins and TNF-α are key cytokines involved in inflammatory responses, while CD163 and Macrophage Inflammatory Proteins indicate macrophage activation. Complement proteins and Matrix Metalloproteinases are involved in immune complex clearance and tissue remodeling, respectively. These biomarkers can help evaluate efficacy of new therapeutics for autoimmune conditions such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), inflammatory bowel disease, ulcerative colitis, Crohn's disease and psoriasis.
Multiplexes with autoimmune-related biomarkers
The biomarkers below have demonstrated links to autoimmune conditions in the scientific literature.