Superoxide Dismutase 1, soluble
Superoxide Dismutase-1 (SOD-1) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including ALS, Down?s Syndrome and Alzheimer?s Disease.
Swiss-Prot Accession Number: P00441