Neuronal Cell Adhesion Molecule

Neuronal Cell Adhesion Molecule (NrCAM) belongs to a family of membrane bound cell adhesion molecules. NrCam mediates adhesion with a number of neuronal adhesion molecules including contactin, TAG-1/contactin-2, neurofascin, and receptor tyrosine phosphatase ?. NrCAM has been implicated in the axogenesis of multiple neuronal populations including sensory axons and commissural axons in the spinal cord. It also plays a role in cerebellar granule cell development and is required in node of Ranvier formation along myelin sheaths.

Swiss-Prot Accession Number: Q92823