Monocyte Chemotactic Protein 1
Monocyte Chemotactic Protein 1
Monocyte Chemotactic Protein 1 (MCP-1; CCL2) plays a role in the recruitment of monocytes to sites of injury and infection. MCP-1 has been found in the joints of people with rheumatoid arthritis where it may serve to recruit macrophages and perpetuate the inflammation in the joints. MCP-1 is also elevated in the urine of lupus patients as a sign of inflammation of the kidney. MCP-1 has also been called small inducible cytokine A2 (SCYA2) and monocyte chemotactic and activating factor (MCAF).
Swiss-Prot Accession Number: P13500
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