Kidney Injury Molecule-1 Simoa

Kidney Injury Molecule-1 (KIM-1) is an immunoglobulin superfamily cell-surface protein that is highly upregulated on the surface of injured kidney epithelial cells. It is also known as TIM-1 (T cell immunoglobulin mucin domains?1), as it is expressed at low levels by subpopulations of activated T cells and hepatitis A virus cellular receptor?1 (HAVCR-1). KIM-1 expression is increased more than any other protein in the injured kidney and is localized predominantly to the apical membrane of the surviving proximal epithelial cells.

Swiss-Prot Accession Number: Q96D42