Interferon-inducible T-cell alpha chemoattractant (ITAC, CXCL11) is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus and spleen. Gene expression of ITAC/CXCL11 is strongly induced by IFN-gamma and IFN- beta, and weakly induced by IFN-alpha. ITAC/CXCL11 is chemotactic for activated T cells. It may play role in CNS diseases and skin immune responses.
Swiss-Prot Accession Number: O14625
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