Interleukin-16 (IL-16) was described originally as lymphocyte chemoattractant factor (LCF), which acts as a chemoattractant for CD4 (+) T-cells, macrophages, and eosinophils. The protein is produced by lymphocytes, eosinophils, mast cells, and lung epithelium. Fibroblasts from several tissues can express IL-16. Very high levels are produced in response to IL-1-beta.
Swiss-Prot Accession Number: Q14005
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