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Interleukin-16

Interleukin-16

Interleukin-16 (IL-16) was described originally as lymphocyte chemoattractant factor (LCF), which acts as a chemoattractant for CD4 (+) T-cells, macrophages, and eosinophils. The protein is produced by lymphocytes, eosinophils, mast cells, and lung epithelium. Fibroblasts from several tissues can express IL-16. Very high levels are produced in response to IL-1-beta.

Swiss-Prot Accession Number: Q14005


Bibliography

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Integrative Omics Approach Identifies Interleukin-16 as a Biomarker of Emphysema (2013) Bowler RP, Bahr TM, Hughes G, Lutz S, Kim YI, Coldren CD, Reisdorph N, Kechris KJ OMICS. 2013 Oct 19. [Epub ahead of print]

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Identification of blood protein biomarkers that aid in the clinical assessment of patients with malignant glioma (2012) Xu BJ, An QA, Srinivasa Gowda S, Yan W, Pierce LA, Abel TW, Rush SZ, Cooper MK, Ye F, Shyr Y, Weaver KD, Thompson RC Int J Oncol. 2012 Jun;40(6):1995-2003

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