Granulocyte Colony-Stimulating Factor

Granulocyte Colony-Stimulating Factor (G-CSF) is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly and acts in hematopoiesis by controlling the production, differentiation, and function of white cell populations of the blood, the granulocytes and the monocytes-macrophages. It is therapeutically available under the names Neupogen or Granulokine (Amgen/Roche) and Granocyte (Rhone-Poulenc) and is used to treat neutropenia (a disorder characterized by an extremely low number of neutrophils in blood).

Swiss-Prot Accession Number: P09919