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Ferritin

Ferritin

Ferritin (FRTN) is found in serum at low concentrations and is directly proportional to the bodys iron stores. In general, variations in total body iron stores will be reflected in the serum ferritin level. Serum ferritin levels are very helpful in the evaluation of iron deficiency anemia, anemia of chronic infection, thalassemia, and hemochromatosis. Serum ferritin levels however, can be nonspecifically elevated in patients with inflammation and or liver disease, regardless of iron stores. This is attributed to hepatocellular leakage of ferritin from damaged cells. Swiss-Prot Accession Number: Heavy chain P02794; Light chain P02792.

Swiss-Prot Accession Number: P02794, P02792


Bibliography

Inflammatory profile analysis reveals differences in cytokine expression between smokers, moist snuff users, and dual users compared to non-tobacco consumers. (2017) Sgambato JA, Jones BA, Caraway JW, Prasad GL Cytokine

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Ferritin levels in the cerebrospinal fluid predict Alzheimers disease outcomes and are regulated by APOE. (2015) Ayton S, Faux NG, Bush AI; Alzheimers Disease Neuroimaging Initiative. Nat Commun. 2015 May 19;6:6760. doi: 10.1038/ncomms7760.

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