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Fibrinogen

Fibrinogen

Fibrinogen is a plasma glycoprotein that is the final common reaction of the coagulation cascade after thrombin cleaves soluble fibrinogen to form fibrin. Low levels of fibrinogen are seen in association with fibrinolysis and liver disease. A high level of fibrinogen is a risk factor for thrombosis and is a strong predictor of cardiovascular risk and stroke, particularly in young adults. Low-dose heparin and ACE-inhibitors reduce fibrinogen and the risk of adverse cardiovascular events. Swiss-Prot Accession Number: Alpha chain P02671; Beta chain P02675; Gamma chain P02679.

Swiss-Prot Accession Number: P02671, P02675, P02679


Bibliography

Identifying the molecular and cellular signature of cardiac dilation following myocardial infarction (2018) Lindsey ML, Ma Y, Flynn ER, Winniford MD, Hall ME, DeLeon-Pennell KY BBA - Molecular Basis of Disease

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A randomised, placebo-controlled trial of anti-interleukin-1 receptor 1 monoclonal antibody MEDI8968 in chronic obstructive pulmonary disease. (2017) Calverley PMA, Sethi S, Dawson M, Ward CK, Finch DK, Penney M, Newbold P, van der Merwe R Respir Res.

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Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke (2016) Oviedo A, Lebrun S, Kogel U, Ho J, Tan WT, Titz B, Leroy P, Vuillaume G, Bera M, Martin F, Rodrigo G, Esposito M, Dempsey R, Ivanov NV, Hoeng J, Peitsch MC, Vanscheeuwijck P. Regul Toxicol Pharmacol.

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Novel data-mining approach identifies biomarkers for diagnosis of Kawasaki disease (2015) Tremoulet AH, Dutkowski J, Sato Y, Kanegaye JT, Ling XB, Burns JC Pediatr Res.

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Multiplexed protein profiling after bariatric surgery: characterization of improved endothelial dysfunction (2013) Bachmayer C, Hammes HP, Hasenberg T, Lammert A, Crowther D, Hess S Experimental and Clinical Endocrinology & Diabetes

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Altered lung function relates to inflammation in an acute LPS mouse model (2012) H?kansson HF, Smailag A, Brunmark C, Miller-Larsson A, Lal H Pulmonary Pharmacology & Therapeutics

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Endothelial activation markers in anemic non-dialysis chronic kidney disease patients. (2008) Patel TV, Mittal BV, Keithi-Reddy SR, Duffield JS, Singh AK Nephron Clin Pract 110: c244-250.

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