E-Selectin, also known as CD62E antigen, is a cell adhesion molecule expressed only on cytokine activated endothelial cells. Soluble E-Selectin arises from proteolytic cleavage of the surface-expressed molecule. It is found in serum and plasma of healthy individuals, with elevated levels seen in certain immune conditions. Its role as a pro-inflammatory molecule is unclear.
Swiss-Prot Accession Number: P16581
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