Cancer Antigen 15-3 a mucin involved in cell adhesion is over-expressed and aberrantly glycosylated in various cancers and is used to detect recurrence and monitor treatment in breast cancer patients. Evidence exists that CA 15-3 is over-expressed to a greater extent than CA-125 in all subtypes of ovarian cancer. High levels are associated with breast, ovarian, prostate and lung cancers as well as non-cancerous ovarian disease.
Swiss-Prot Accession Number: P15941
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