Alpha-2-Macroglobulin (A2M) is a major plasma protein in humans with various functions including ion transport, carrier protein, and the inhibition of proteinases. Elevated levels are seen in clinical conditions such as cirrhosis, nephrotic syndrome, severe burns and diabetes. Decreased levels are seen in pancreatitis, fibrinolysis, and liver disease.
Swiss-Prot Accession Number: P01023
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